CD2AP (NM_012120) Human Recombinant Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 71.3 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_036252 |
| Locus ID | 23607 |
| UniProt ID | Q9Y5K6 |
| Cytogenetics | 6p12.3 |
| RefSeq Size | 5425 |
| RefSeq ORF | 1917 |
| Synonyms | CMS |
| Summary | This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease. provided by RefSeq, Jul 2008 |
| Protein Categories | Cytokines, Growth Factors, Intracellular Proteins |
| Protein Families | Druggable Genome |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "CD2AP" proteins (3)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH310191 | CD2AP MS Standard C13 and N15-labeled recombinant protein (NP_036252) | 10 ug |
$3,360.00
|
|
| LC415971 | Lyophilized CD2AP HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY415971 | Transient overexpression lysate of CD2-associated protein (CD2AP) (as WB positive control) | 100 ug |
$436.00
|
|
Citations
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