PPM1F (NM_014634) Human Recombinant Protein
SKU
TP310043
Recombinant protein of human protein phosphatase 1F (PP2C domain containing) (PPM1F), 20 µg
$867.00
In Stock*
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 49.7 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_055449 |
| Locus ID | 9647 |
| UniProt ID | P49593 |
| Cytogenetics | 22q11.22 |
| RefSeq Size | 5199 |
| RefSeq ORF | 1359 |
| Synonyms | CAMKP; CaMKPase; FEM-2; hFEM-2; POPX2 |
| Summary | The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus block the effects of p21-activated kinase 1 (PAK), a protein kinase mediating biological effects downstream of Rho GTPases. Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase. The overexpression of this phosphatase or CAMK2G has been shown to mediate caspase-dependent apoptosis. An alternatively spliced transcript variant has been identified, but its full-length nature has not been determined. provided by RefSeq, Jul 2008 |
| Protein Categories | Growth Factors, Intracellular Proteins |
| Protein Families | Druggable Genome, Phosphatase |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "PPM1F" proteins (3)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH310043 | PPM1F MS Standard C13 and N15-labeled recombinant protein (NP_055449) | 10 ug |
$3,360.00
|
|
| LC402357 | Lyophilized PPM1F HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY402357 | Transient overexpression lysate of protein phosphatase 1F (PP2C domain containing) (PPM1F) (as WB positive control) | 100 ug |
$436.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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