IRF3 (NM_001571) Human Recombinant Protein

CAT#: TP309951

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Recombinant protein of human interferon regulatory factor 3 (IRF3)


 Product Datasheet for 'TP309951'

  View other "IRF3" proteins (11)

USD 748.00


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Size
    • 20 ug


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Specifications

Product Data
Description Recombinant protein of human interferon regulatory factor 3 (IRF3)
Species Human
Expression Host HEK293T
Tag C-Myc/DDK
Predicted MW 47 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Reference Data
RefSeq NP_001562
Locus ID 3661
Refseq Size 1626
Cytogenetics 19q13.33
Refseq ORF 1281
Synonyms IIAE7
Summary This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]
Protein Families Druggable Genome, Transcription Factors
Protein Pathways Cytosolic DNA-sensing pathway, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway

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