IRF3 (NM_001571) Human Mass Spec Standard

SKU
PH309951
IRF3 MS Standard C13 and N15-labeled recombinant protein (NP_001562)
  $3,360.00
3 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC209951
Predicted MW 47.2 kDa
Protein Sequence
Protein Sequence
>RC209951 protein sequence
Red=Cloning site Green=Tags(s)

MGTPKPRILPWLVSQLDLGQLEGVAWVNKSRTRFRIPWKHGLRQDAQQEDFGIFQAWAEATGAYVPGRDK
PDLPTWKRNFRSALNRKEGLRLAEDRSKDPHDPHKIYEFVNSGVGDFSQPDTSPDTNGGGSTSDTQEDIL
DELLGNMVLAPLPDPGPPSLAVAPEPCPQPLRSPSLDNPTPFPNLGPSENPLKRLLVPGEEWEFEVTAFY
RGRQVFQQTISCPEGLRLVGSEVGDRTLPGWPVTLPDPGMSLTDRGVMSYVRHVLSCLGGGLALWRAGQW
LWAQRLGHCHTYWAVSEELLPNSGHGPDGEVPKDKEGGVFDLGPFIVDLITFTEGSGRSPRYALWFCVGE
SWPQDQPWTKRLVMVKVVPTCLRALVEMARVGGASSLENTVDLHISNSHPLSLTSDQYKAYLQDLVEGMD
FQGPGES

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_001562
RefSeq Size 1626
RefSeq ORF 1281
Synonyms IIAE7
Locus ID 3661
UniProt ID Q14653
Cytogenetics 19q13.33
Summary This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. The protein plays an important role in the innate immune response against DNA and RNA viruses. Mutations in this gene are associated with Encephalopathy, acute, infection-induced, herpes-specific, 7. provided by RefSeq, Sep 2020
Protein Families Druggable Genome, Transcription Factors
Protein Pathways Cytosolic DNA-sensing pathway, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway
Reviews
 
 
 
 
 

Be the first to review this product

Please note:
Only reviews with images are eligible for a $20/20€ Amazon gift card.
Reviews without images are eligible for a $10/10€ Amazon gift card.
For more details about the terms and conditions, please visit the promotion page.

Review image
Documents
Resources
Other "IRF3" proteins (8)
SKU Description Size Price
LC400600 Lyophilized IRF3 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC434143 Lyophilized IRF3 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC434202 Lyophilized IRF3 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY400600 Transient overexpression lysate of interferon regulatory factor 3 (IRF3) (as WB positive control) 100 ug
$436.00
LY434143 Transient overexpression lysate of interferon regulatory factor 3 (IRF3), transcript variant 4 (as WB positive control) 100 ug
$436.00
LY434202 Transient overexpression lysate of interferon regulatory factor 3 (IRF3), transcript variant 3 (as WB positive control) 100 ug
$436.00
TP309951 Recombinant protein of human interferon regulatory factor 3 (IRF3), 20 µg 20 ug
$737.00
TP331144 Purified recombinant protein of Homo sapiens interferon regulatory factor 3 (IRF3), transcript variant 4, 20 µg 20 ug
$737.00

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Related Products