IRF3 (NM_001571) Human Mass Spec Standard
Specifications
| Product Data | |
| Tag | C-Myc/DDK |
|---|---|
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC209951 |
| Predicted MW | 47.2 kDa |
| Protein Sequence | |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
| Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_001562 |
| RefSeq Size | 1626 |
| RefSeq ORF | 1281 |
| Synonyms | IIAE7 |
| Locus ID | 3661 |
| UniProt ID | Q14653 |
| Cytogenetics | 19q13.33 |
| Summary | This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. The protein plays an important role in the innate immune response against DNA and RNA viruses. Mutations in this gene are associated with Encephalopathy, acute, infection-induced, herpes-specific, 7. provided by RefSeq, Sep 2020 |
| Protein Families | Druggable Genome, Transcription Factors |
| Protein Pathways | Cytosolic DNA-sensing pathway, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "IRF3" proteins (8)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| LC400600 | Lyophilized IRF3 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC434143 | Lyophilized IRF3 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC434202 | Lyophilized IRF3 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY400600 | Transient overexpression lysate of interferon regulatory factor 3 (IRF3) (as WB positive control) | 100 ug |
$436.00
|
|
| LY434143 | Transient overexpression lysate of interferon regulatory factor 3 (IRF3), transcript variant 4 (as WB positive control) | 100 ug |
$436.00
|
|
| LY434202 | Transient overexpression lysate of interferon regulatory factor 3 (IRF3), transcript variant 3 (as WB positive control) | 100 ug |
$436.00
|
|
| TP309951 | Recombinant protein of human interferon regulatory factor 3 (IRF3), 20 µg | 20 ug |
$737.00
|
|
| TP331144 | Purified recombinant protein of Homo sapiens interferon regulatory factor 3 (IRF3), transcript variant 4, 20 µg | 20 ug |
$737.00
|
|
Citations
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