FOXO3 (NM_001455) Human Recombinant Protein
$737.00
In Stock*
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 71.1 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Bioactivity | Binding assay (PMID: 26561547) |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_001446 |
| Locus ID | 2309 |
| UniProt ID | O43524 |
| Cytogenetics | 6q21 |
| RefSeq Size | 3338 |
| RefSeq ORF | 2019 |
| Synonyms | AF6q21; FKHRL1; FKHRL1P2; FOXO2; FOXO3A |
| Summary | This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed. provided by RefSeq, Jul 2008 |
| Protein Categories | Intracellular Proteins, Transciption Factors |
| Protein Families | Druggable Genome, Transcription Factors |
| Protein Pathways | Chemokine signaling pathway, Endometrial cancer, Neurotrophin signaling pathway, Non-small cell lung cancer |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "FOXO3" proteins (7)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH302894 | FOXO3 MS Standard C13 and N15-labeled recombinant protein (NP_963853) | 10 ug |
$3,360.00
|
|
| PH309846 | FOXO3 MS Standard C13 and N15-labeled recombinant protein (NP_001446) | 10 ug |
$3,360.00
|
|
| LC400566 | Lyophilized FOXO3 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC404461 | Lyophilized FOXO3 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY400566 | Transient overexpression lysate of forkhead box O3 (FOXO3), transcript variant 1 (as WB positive control) | 100 ug |
$436.00
|
|
| LY404461 | Transient overexpression lysate of forkhead box O3 (FOXO3), transcript variant 2 (as WB positive control) | 100 ug |
$436.00
|
|
| TP302894 | Recombinant protein of human forkhead box O3 (FOXO3), transcript variant 2, 20 µg | 20 ug |
$737.00
|
|
Citations
FOXO3-NF-κB RelA Protein Complexes Reduce Proinflammatory Cell Signaling and Function
Thompson, Larson, Vidrine et al
J. Immunol. (2015)
Thompson, Larson, Vidrine et al
J. Immunol. (2015)
Cited by 54
Showing 1-1 of 1 papers.
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in shipping.
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