CNOT7 (NM_013354) Human Recombinant Protein

CAT#: TP309293

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Recombinant protein of human CCR4-NOT transcription complex, subunit 7 (CNOT7), transcript variant 1


 Product Datasheet for 'TP309293'

  View other "CNOT7" proteins (7)

USD 748.00


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Size
    • 20 ug


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Specifications

Product Data
Description Recombinant protein of human CCR4-NOT transcription complex, subunit 7 (CNOT7), transcript variant 1
Species Human
Expression Host HEK293T
Tag C-Myc/DDK
Predicted MW 32.6 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Reference Data
RefSeq NP_037486
Locus ID 29883
Refseq Size 2646
Cytogenetics 8p22
Refseq ORF 855
Synonyms CAF-1; CAF1; Caf1a; hCAF-1
Summary The protein encoded by this gene binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The encoded protein downregulates the innate immune response and therefore provides a therapeutic target for enhancing its antimicrobial activity against foreign agents. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and X. [provided by RefSeq, Apr 2016]
Protein Families Transcription Factors
Protein Pathways RNA degradation

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