BACE1 (NM_012104) Human Recombinant Protein

CAT#: TP309115

Recombinant protein of human beta-site APP-cleaving enzyme 1 (BACE1), transcript variant a

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 Product Datasheet for 'TP309115'

USD 680.00


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Size
    • 20 ug

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Specifications

Product Data
Description Recombinant protein of human beta-site APP-cleaving enzyme 1 (BACE1), transcript variant a
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence Recombinant protein was produced with TrueORF clone, RC209115. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag C-MYC/DDK
Predicted MW 51 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Reference Data
RefSeq NP_036236
Locus ID 23621
Refseq Size 5850
Cytogenetics 11q23.3
Refseq ORF 1503
Synonyms ASP2; BACE; HSPC104
Summary This gene encodes a member of the peptidase A1 family of aspartic proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protease. This transmembrane protease catalyzes the first step in the formation of amyloid beta peptide from amyloid precursor protein. Amyloid beta peptides are the main constituent of amyloid beta plaques, which accumulate in the brains of human Alzheimer's disease patients. [provided by RefSeq, Nov 2015].
Protein Families
Protein Pathways
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