TCCR (IL27RA) (NM_004843) Human Recombinant Protein

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SKU
TP307012
Recombinant protein of human interleukin 27 receptor, alpha (IL27RA), 20 µg
  $737.00
4 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
>Peptide sequence encoded by RC207012
Blue=ORF Red=Cloning site Green=Tag(s)

MRGGRGAPFWLWPLPKLALLPLLWVLFQRTRPQGSAGPLQCYGVGPLGDLNCSWEPLGDLGAPSELHLQ
SQKYRSNKTQTVAVAAGRSWVAIPREQLTMSDKLLVWGTKAGQPLWPPVFVNLETQMKPNAPRLGPDVD
FSEDDPLEATVHWAPPTWPSHKVLICQFHYRRCQEAAWTLLEPELKTIPLTPVEIQDLELATGYKVYGR
CRMEKEEDLWGEWSPILSFQTPPSAPKDVWVSGNLCGTPGGEEPLLLWKAPGPCVQVSYKVWFWVGGRE
LSPEGITCCCSLIPSGAEWARVSAVNATSWEPLTNLSLVCLDSASAPRSVAVSSIAGSTELLVTWQPGP
GEPLEHVVDWARDGDPLEKLNWVRLPPGNLSALLPGNFTVGVPYRITVTAVSASGLASASSVWGFREEL
APLVGPTLWRLQDAPPGTPAIAWGEVPRHQLRGHLTHYTLCAQSGTSPSVCMNVSGNTQSVTLPDLPWG
PCELWVTASTIAGQGPPGPILRLHLPDNTLRWKVLPGILFLWGLFLLGCGLSLATSGRCYHLRHKVLPR
WVWEKVPDPANSSSGQPHMEQVPEAQPLGDLPILEVEEMEPPPVMESSQPAQATAPLDSGYEKHFLPTP
EELGLLGPPRPQVLA

SGPTRTRPLEQKLISEEDLAANDILDYKDDDDKV

Recombinant protein using RC207012 also available, TP307012
Tag C-Myc/DDK
Predicted MW 69.3 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_004834
Locus ID 9466
UniProt ID Q6UWB1
Cytogenetics 19p13.12
RefSeq Size 3258
RefSeq ORF 1908
Synonyms CRL1; IL-27RA; IL27R; TCCR; WSX1; zcytor1
Summary In mice, CD4+ helper T-cells differentiate into type 1 (Th1) cells, which are critical for cell-mediated immunity, predominantly under the influence of IL12. Also, IL4 influences their differentiation into type 2 (Th2) cells, which are critical for most antibody responses. Mice deficient in these cytokines, their receptors, or associated transcription factors have impaired, but are not absent of, Th1 or Th2 immune responses. This gene encodes a protein which is similar to the mouse T-cell cytokine receptor Tccr at the amino acid level, and is predicted to be a glycosylated transmembrane protein. provided by RefSeq, Jul 2008
Protein Categories Cytokines, Membrane Proteins
Protein Families Druggable Genome, Transmembrane
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Other "TCCR" proteins (3)
SKU Description Size Price
PH307012 IL27RA MS Standard C13 and N15-labeled recombinant protein (NP_004834) 10 ug
$3,360.00
LC417709 Lyophilized IL27RA HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY417709 Transient overexpression lysate of interleukin 27 receptor, alpha (IL27RA) (as WB positive control) 100 ug
$436.00

file-alt Citations

Characterization of HZ0412a, a novel potent humanized anti-IL-6 receptor antibody that blocks IL-6R binding to gp130
Han, Liu, Xu et al
Antib Ther (2023) 6 (2), 119-126 DOI: 10.1093/abt/tbad008
Cited by 5
Snippet: …More recently, elevated IL-6 levels have been found in patients with COVID-19, and the role of IL-6-mediated pr;IL-27Rα (Cat#: TP307012), IL-31Rα (Cat#: TP720674) and IL-17R (Cat#: TP302390) were purchased from Origene. …
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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