STAT4 (NM_003151) Human Recombinant Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 85.8 kDa |
| Concentration | >0.3 mg/mL as determined by microplate BCA method |
| Purity | >90% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 50 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_003142 |
| Locus ID | 6775 |
| UniProt ID | Q14765 |
| Cytogenetics | 2q32.2-q32.3 |
| RefSeq Size | 2840 |
| RefSeq ORF | 2244 |
| Synonyms | SLEB11 |
| Summary | The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein. provided by RefSeq, Aug 2011 |
| Protein Categories | Allergies and autoimmune diseases, Cytokines, Growth Factors, Intracellular Proteins, Transciption Factors |
| Protein Families | Druggable Genome, Transcription Factors |
| Protein Pathways | Jak-STAT signaling pathway |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "STAT4" proteins (3)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH306892 | STAT4 MS Standard C13 and N15-labeled recombinant protein (NP_003142) | 10 ug |
$3,360.00
|
|
| LC401095 | Lyophilized STAT4 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY401095 | Transient overexpression lysate of signal transducer and activator of transcription 4 (STAT4) (as WB positive control) | 100 ug |
$436.00
|
|
Citations
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