STAT4 (NM_003151) Human Mass Spec Standard
Specifications
| Product Data | |
| Tag | C-Myc/DDK |
|---|---|
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC206892 |
| Predicted MW | 85.9 kDa |
| Protein Sequence | |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
| Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_003142 |
| RefSeq Size | 2840 |
| RefSeq ORF | 2244 |
| Synonyms | SLEB11 |
| Locus ID | 6775 |
| UniProt ID | Q14765 |
| Cytogenetics | 2q32.2-q32.3 |
| Summary | The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein. provided by RefSeq, Aug 2011 |
| Protein Families | Druggable Genome, Transcription Factors |
| Protein Pathways | Jak-STAT signaling pathway |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "STAT4" proteins (3)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| LC401095 | Lyophilized STAT4 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY401095 | Transient overexpression lysate of signal transducer and activator of transcription 4 (STAT4) (as WB positive control) | 100 ug |
$436.00
|
|
| TP306892 | Recombinant protein of human signal transducer and activator of transcription 4 (STAT4), 20 µg | 20 ug |
$737.00
|
|
Citations
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