ABCD1 (NM_000033) Human Recombinant Protein

CAT#: TP306885

Recombinant protein of human ATP-binding cassette, sub-family D (ALD), member 1 (ABCD1)

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 Product Datasheet for 'TP306885'

USD 680.00

2 Weeks

    • 20 ug

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Product Data
Description Recombinant protein of human ATP-binding cassette, sub-family D (ALD), member 1 (ABCD1)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence Recombinant protein was produced with TrueORF clone, RC206885. Click on the TrueORF clone link to view cDNA and protein sequences.
Predicted MW 82.8 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Reference Data
RefSeq NP_000024
Locus ID 215
Refseq Size 3616
Cytogenetics Xq28
Refseq ORF 2235
Synonyms ABC42; ALD; ALDP; AMN
Summary The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein is likely involved in the peroxisomal transport or catabolism of very long chain fatty acids. Defects in this gene have been identified as the underlying cause of adrenoleukodystrophy, an X-chromosome recessively inherited demyelinating disorder of the nervous system. [provided by RefSeq, Jul 2008].
Protein Families
Protein Pathways
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