HPD (NM_002150) Human Recombinant Protein

CAT#: TP306860

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Recombinant protein of human 4-hydroxyphenylpyruvate dioxygenase (HPD)


 Product Datasheet for 'TP306860'

  View other "HPD" proteins (8)

USD 748.00


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Size
    • 20 ug


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Specifications

Product Data
Description Recombinant protein of human 4-hydroxyphenylpyruvate dioxygenase (HPD)
Species Human
Expression Host HEK293T
Tag C-Myc/DDK
Predicted MW 44.8 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Reference Data
RefSeq NP_002141
Locus ID 3242
Refseq Size 1440
Cytogenetics 12q24.31
Refseq ORF 1179
Synonyms 4-HPPD; 4HPPD; GLOD3; HPPDASE; PPD
Summary The protein encoded by this gene is an enzyme in the catabolic pathway of tyrosine. The encoded protein catalyzes the conversion of 4-hydroxyphenylpyruvate to homogentisate. Defects in this gene are a cause of tyrosinemia type 3 (TYRO3) and hawkinsinuria (HAWK). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]
Protein Families Druggable Genome
Protein Pathways Metabolic pathways, Phenylalanine metabolism, Tyrosine metabolism, Ubiquinone and other terpenoid-quinone biosynthesis

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Other Versions

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