HPD (NM_002150) Human Recombinant Protein

CAT#: TP306860

Recombinant protein of human 4-hydroxyphenylpyruvate dioxygenase (HPD)

Product images

Specifications

Product Data

• Description: Recombinant protein of human 4-hydroxyphenylpyruvate dioxygenase (HPD)
• Species: Human
• Expression Host: HEK293T
• Tag: C-Myc/DDK
• Predicted MW: 44.8 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.

Reference Data

• RefSeq: NP_002141
• Locus ID: 3242
• Refseq Size: 1440
• Cytogenetics: 12q24.31
• Refseq ORF: 1179
• Synonyms: 4-HPPD; 4HPPD; GLOD3; HPPDASE; PPD
• Summary: The protein encoded by this gene is an enzyme in the catabolic pathway of tyrosine. The encoded protein catalyzes the conversion of 4-hydroxyphenylpyruvate to homogentisate. Defects in this gene are a cause of tyrosinemia type 3 (TYRO3) and hawkinsinuria (HAWK). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]
• Protein Families: Druggable Genome
• Protein Pathways: Metabolic pathways, Phenylalanine metabolism, Tyrosine metabolism, Ubiquinone and other terpenoid-quinone biosynthesis