HSD17B3 (NM_000197) Human Recombinant Protein

CAT#: TP306558

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Recombinant protein of human hydroxysteroid (17-beta) dehydrogenase 3 (HSD17B3)


Product Datasheet for 'TP306558'


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USD 748.00


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Size
    • 20 ug


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Specifications

Product Data
Description Recombinant protein of human hydroxysteroid (17-beta) dehydrogenase 3 (HSD17B3)
Species Human
Expression Host HEK293T
Expression cDNA Clone or AA Sequence Recombinant protein was produced with TrueORF clone, RC206558. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag C-Myc/DDK
Predicted MW 34.3 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_000188
Locus ID 3293
Refseq Size 1134
Cytogenetics 9q22.32
Refseq ORF 930
Synonyms EDH17B3; SDR12C2
Summary This isoform of 17 beta-hydroxysteroid dehydrogenase is expressed predominantly in the testis and catalyzes the conversion of androstenedione to testosterone. It preferentially uses NADP as cofactor. Deficiency can result in male pseudohermaphroditism with gynecomastia. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, Transmembrane
Protein Pathways Androgen and estrogen metabolism, Metabolic pathways

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