ALS (IGFALS) (NM_004970) Human Recombinant Protein

CAT#: TP306542

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Recombinant protein of human insulin-like growth factor binding protein, acid labile subunit (IGFALS)


 Product Datasheet for 'TP306542'

 Cited in 1 publication.

  View other "IGFALS" proteins (3)

USD 748.00


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Size
    • 20 ug


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Specifications

Product Data
Description Recombinant protein of human insulin-like growth factor binding protein, acid labile subunit (IGFALS)
Species Human
Expression Host HEK293T
Tag C-Myc/DDK
Predicted MW 63.2 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Reference Data
RefSeq NP_004961
Locus ID 3483
Refseq Size 2168
Cytogenetics 16p13.3
Refseq ORF 1815
Synonyms ACLSD; ALS
Summary The protein encoded by this gene is a serum protein that binds insulin-like growth factors, increasing their half-life and their vascular localization. Production of the encoded protein, which contains twenty leucine-rich repeats, is stimulated by growth hormone. Defects in this gene are a cause of acid-labile subunit deficiency, which maifests itself in a delayed and slow puberty. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
Protein Families Druggable Genome, Secreted Protein

Citations (1)

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Other Versions

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