CLIC2 (NM_001289) Human Recombinant Protein

CAT#: TP304727

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Recombinant protein of human chloride intracellular channel 2 (CLIC2)


 Product Datasheet for 'TP304727'

 Cited in 1 publication.

  View other "CLIC2" proteins (6)

USD 748.00


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Size
    • 20 ug


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Specifications

Product Data
Description Recombinant protein of human chloride intracellular channel 2 (CLIC2)
Species Human
Expression Host HEK293T
Tag C-Myc/DDK
Predicted MW 28.2 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Bioactivity ELISA capture for autoantibodies (PMID: 28862243)
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Reference Data
RefSeq NP_001280
Locus ID 1193
Refseq Size 2694
Cytogenetics Xq28
Refseq ORF 741
Synonyms CLIC2b; MRXS32; XAP121
Summary This gene encodes a chloride intracellular channel protein. Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. This protein plays a role in inhibiting the function of ryanodine receptor 2. A mutation in this gene is the cause of an X-linked form of cognitive disability. [provided by RefSeq, Jul 2017]
Protein Families Druggable Genome, Ion Channels: Other

Citations (1)

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