AP2 alpha (TFAP2A) (NM_001032280) Human Recombinant Protein
SKU
TP304603
Recombinant protein of human transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) (TFAP2A), transcript variant 2, 20 µg
$867.00
In Stock*
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 47 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Bioactivity | EMSA reaction positive control (PMID: 27866707) |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_001027451 |
| Locus ID | 7020 |
| UniProt ID | P05549 |
| Cytogenetics | 6p24.3 |
| RefSeq Size | 3808 |
| RefSeq ORF | 1293 |
| Synonyms | AP-2; AP-2alpha; AP2TF; BOFS; TFAP2 |
| Summary | The protein encoded by this gene is a transcription factor that binds the consensus sequence 5'-GCCNNNGGC-3'. The encoded protein functions as either a homodimer or as a heterodimer with similar family members. This protein activates the transcription of some genes while inhibiting the transcription of others. Defects in this gene are a cause of branchiooculofacial syndrome (BOFS). Three transcript variants encoding different isoforms have been found for this gene.provided by RefSeq, Dec 2009 |
| Protein Categories | Intracellular Proteins, Transciption Factors |
| Protein Families | Druggable Genome, Transcription Factors |
Reviews
Documents
| FAQs |
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Resources
| Recombinant Protein Resources |
Other "AP2 alpha" proteins (5)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH304603 | TFAP2A MS Standard C13 and N15-labeled recombinant protein (NP_001027451) | 10 ug |
$3,360.00
|
|
| LC420895 | Lyophilized TFAP2A HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC422292 | Lyophilized TFAP2A HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY420895 | Transient overexpression lysate of transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) (TFAP2A), transcript variant 3 (as WB positive control) | 100 ug |
$665.00
|
|
| LY422292 | Transient overexpression lysate of transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) (TFAP2A), transcript variant 2 (as WB positive control) | 100 ug |
$436.00
|
|
Citations
A Functional Variant Associated with Atrial Fibrillation Regulates PITX2c Expression through TFAP2a
Ye, Tucker, Weng et al
Am. J. Hum. Genet. (2016) 99 (6), 1281-1291 DOI: 10.1016/j.ajhg.2016.10.001
Ye, Tucker, Weng et al
Am. J. Hum. Genet. (2016) 99 (6), 1281-1291 DOI: 10.1016/j.ajhg.2016.10.001
AI Summary: OriGene’s purified TFAP2a protein was used in binding assays to investigate how the transcription factor interacts with regulatory DNA sequences near the PITX2c gene, helping to elucidate the molecular mechanism by which the AF-associated SNP rs2595104 affects gene expression.
Snippet: Pierce). In brief, the double-stranded probes (20 fmol) were incubated withpurified TFAP2a (Origene) at room temperature for 20 min in the presence of 100 mMTris (pH 7.5), 500 mM KCl, and 10 mM DTT in a 20 L reaction. ... Cite SaveSaving
Showing 1-1 of 1 papers.
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complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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