DPM2 (NM_003863) Human Recombinant Protein

CAT#: TP303919

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Recombinant protein of human dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit (DPM2)


 Product Datasheet for 'TP303919'

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USD 748.00


Availability*
3 Weeks

Size
    • 20 ug


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Specifications

Product Data
Description Recombinant protein of human dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit (DPM2)
Species Human
Expression Host HEK293T
Tag C-Myc/DDK
Predicted MW 9.1 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Reference Data
RefSeq NP_003854
Locus ID 8818
Refseq Size 1561
Cytogenetics 9q34.11
Refseq ORF 252
Synonyms CDG1U
Summary Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. The protein encoded by this gene is a hydrophobic protein that contains 2 predicted transmembrane domains and a putative ER localization signal near the C terminus. This protein associates with DPM1 in vivo and is required for the ER localization and stable expression of DPM1 and also enhances the binding of dolichol-phosphate to DPM1. [provided by RefSeq, Jul 2008]
Protein Families Transmembrane
Protein Pathways Glycosylphosphatidylinositol(GPI)-anchor biosynthesis, Metabolic pathways, N-Glycan biosynthesis

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68 Mouse Clones
HUMAN PROREINS 101