DPM2 (NM_003863) Human Mass Spec Standard
Specifications
| Product Data | |
| Tag | C-Myc/DDK |
|---|---|
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC203919 |
| Predicted MW | 9.3 kDa |
| Protein Sequence | |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
| Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_003854 |
| RefSeq Size | 1561 |
| RefSeq ORF | 252 |
| Synonyms | CDG1U |
| Locus ID | 8818 |
| UniProt ID | O94777 |
| Cytogenetics | 9q34.11 |
| Summary | Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. The protein encoded by this gene is a hydrophobic protein that contains 2 predicted transmembrane domains and a putative ER localization signal near the C terminus. This protein associates with DPM1 in vivo and is required for the ER localization and stable expression of DPM1 and also enhances the binding of dolichol-phosphate to DPM1. provided by RefSeq, Jul 2008 |
| Protein Families | Transmembrane |
| Protein Pathways | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis, Metabolic pathways, N-Glycan biosynthesis |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "DPM2" proteins (3)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| LC418387 | Lyophilized DPM2 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY418387 | Transient overexpression lysate of dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit (DPM2) (as WB positive control) | 100 ug |
$436.00
|
|
| TP303919 | Recombinant protein of human dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit (DPM2), 20 µg | 20 ug |
$867.00
|
|
Citations
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