ROR alpha (RORA) (NM_134261) Human Recombinant Protein

CAT#: TP302926

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Recombinant protein of human RAR-related orphan receptor A (RORA), transcript variant 1


 Product Datasheet for 'TP302926'

 Cited in 1 publication.

  View other "RORA" proteins (7)

USD 748.00


Availability*
2 Weeks

Size
    • 20 ug


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Specifications

Product Data
Description Recombinant protein of human RAR-related orphan receptor A (RORA), transcript variant 1
Species Human
Expression Host HEK293T
Tag C-Myc/DDK
Predicted MW 58.8 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Reference Data
RefSeq NP_599023
Locus ID 6095
Refseq Size 1847
Cytogenetics 15q22.2
Refseq ORF 1569
Synonyms IDDECA; NR1F1; ROR1; ROR2; ROR3; RZR-ALPHA; RZRA
Summary The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The encoded protein has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Also, it has been shown to aid in the transcriptional regulation of some genes involved in circadian rhythm. Four transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2014]
Protein Families Druggable Genome, Nuclear Hormone Receptor, Transcription Factors

Citations (1)

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