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Optineurin (OPTN) (NM_001008211) Human Recombinant Protein

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SKU
TP302470
Recombinant protein of human optineurin (OPTN), transcript variant 1, 20 µg
Size:
20 ug 1 mg 100 ug
  $737.00
In Stock*
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Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
>RC202470 protein sequence
Red=Cloning site Green=Tags(s)

MSHQPLSCLTEKEDSPSESTGNGPPHLAHPNLDTFTPEELLQQMKELLTENHQLKEAMKLNNQAMKGRFE
ELSAWTEKQKEERQFFEIQSKEAKERLMALSHENEKLKEELGKLKGKSERSSEDPTDDSRLPRAEAEQEK
DQLRTQVVRLQAEKADLLGIVSELQLKLNSSGSSEDSFVEIRMAEGEAEGSVKEIKHSPGPTRTVSTGTA
LSKYRSRSADGAKNYFEHEELTVSQLLLCLREGNQKVERLEVALKEAKERVSDFEKKTSNRSEIETQTEG
STEKENDEEKGPETVGSEVEALNLQVTSLFKELQEAHTKLSEAELMKKRLQEKCQALERKNSAIPSELNE
KQELVYTNKKLELQVESMLSEIKMEQAKTEDEKSKLTVLQMTHNKLLQEHNNALKTIEELTRKESEKVDR
AVLKELSEKLELAEKALASKQLQMDEMKQTIAKQEEDLETMTILRAQMEVYCSDFHAERAAREKIHEEKE
QLALQLAVLLKENDAFEDGGRQSLMEMQSRHGARTSDSDQQAYLVQRGAEDRDWRQQRNIPIHSCPKCGE
VLPDIDTLQIHVMDCII

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag C-Myc/DDK
Predicted MW 65.7 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_001008212
Locus ID 10133
UniProt ID Q96CV9
Cytogenetics 10p13
RefSeq Size 3597
RefSeq ORF 1731
Synonyms ALS12; FIP2; GLC1E; HIP7; HYPL; NRP; TFIIIA-INTP
Summary This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein. provided by RefSeq, Jul 2008
Protein Categories Intracellular Proteins, Nervous system: Neurodegenerative diseases
Protein Families Druggable Genome
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Other "Optineurin" proteins (13)
SKU Description Size Price
PH302470 OPTN MS Standard C13 and N15-labeled recombinant protein (NP_001008212) 10 ug
$3,360.00
LC411824 Lyophilized OPTN HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC423390 Lyophilized OPTN HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC423391 Lyophilized OPTN HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC423392 Lyophilized OPTN HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC425228 Lyophilized OPTN HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC425229 Lyophilized OPTN HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY411824 Transient overexpression lysate of optineurin (OPTN), transcript variant 2 (as WB positive control) 100 ug
$436.00
LY423390 Transient overexpression lysate of optineurin (OPTN), transcript variant 1 (as WB positive control) 100 ug
$436.00
LY423391 Transient overexpression lysate of optineurin (OPTN), transcript variant 3 (as WB positive control) 100 ug
$665.00
LY423392 Transient overexpression lysate of optineurin (OPTN), transcript variant 4 (as WB positive control) 100 ug
$665.00
LY425228 Transient overexpression lysate of optineurin (OPTN), transcript variant 3 (as WB positive control) 100 ug
$436.00
LY425229 Transient overexpression lysate of optineurin (OPTN), transcript variant 4 (as WB positive control) 100 ug
$436.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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