Optineurin (OPTN) Mouse Monoclonal Antibody [Clone ID: OTI7H2]

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SKU
TA812132
OPTN mouse monoclonal antibody,clone OTI7H2
  $447.00
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Specifications
Specifications
Product Data
Clone Name OTI7H2
Application IHC, WB
Recommended Dilution WB 1:2000, IHC 1:500
Reactivity Human
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human OPTN (NP_001008212) produced in HEK293T cell.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 65.7 kDa
Gene Name optineurin
Database Link
Background This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein. provided by RefSeq, Jul 2008
Synonyms ALS12; FIP2; GLC1E; HIP7; HYPL; NRP; TFIIIA-INTP
Reference Data
Protein Categories Intracellular Proteins, Nervous system: Neurodegenerative diseases
Protein Families Druggable Genome
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Other "OTI7H2" antibodies (4)
SKU Description Size Price
CF812132 Carrier-free (BSA/glycerol-free) OPTN mouse monoclonal antibody,clone OTI7H2 100 ug
$620.00
TA812132AM OPTN mouse monoclonal antibody,clone OTI7H2, Biotinylated 100 ul
$509.00
TA812132BM OPTN mouse monoclonal antibody,clone OTI7H2, HRP conjugated 100 ul
$509.00
TA812132S OPTN mouse monoclonal antibody,clone OTI7H2 30 ul
$200.00

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