SAE1 (NM_005500) Human Recombinant Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 38.3 kDa |
| Concentration | >0.1 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Bioactivity | ELISA capture for autoantibodies (PMID: 28298642) |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_005491 |
| Locus ID | 10055 |
| UniProt ID | Q9UBE0 |
| Cytogenetics | 19q13.32 |
| RefSeq Size | 2538 |
| RefSeq ORF | 1038 |
| Synonyms | AOS1; HSPC140; SUA1; UBLE1A |
| Summary | Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 and UBA2 (MIM 613295) form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 PubMed 9920803).supplied by OMIM, Mar 2010 |
| Protein Categories | Intracellular Proteins |
| Protein Pathways | Ubiquitin mediated proteolysis |
Reviews
Documents
| FAQs |
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Resources
| Recombinant Protein Resources |
Other "SAE1" proteins (11)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH301820 | SAE1 MS Standard C13 and N15-labeled recombinant protein (NP_005491) | 10 ug |
$3,360.00
|
|
| PH326908 | SAE1 MS Standard C13 and N15-labeled recombinant protein (NP_001139185) | 10 ug |
$3,360.00
|
|
| PH327950 | SAE1 MS Standard C13 and N15-labeled recombinant protein (NP_057486) | 10 ug |
$3,360.00
|
|
| LC401688 | Lyophilized SAE1 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC428977 | Lyophilized SAE1 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC429497 | Lyophilized SAE1 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY401688 | Transient overexpression lysate of SUMO1 activating enzyme subunit 1 (SAE1), transcript variant 1 (as WB positive control) | 100 ug |
$436.00
|
|
| LY428977 | Transient overexpression lysate of SUMO1 activating enzyme subunit 1 (SAE1), transcript variant 2 (as WB positive control) | 100 ug |
$436.00
|
|
| LY429497 | Transient overexpression lysate of SUMO1 activating enzyme subunit 1 (SAE1), transcript variant 1 (as WB positive control) | 100 ug |
$436.00
|
|
| TP326908 | Purified recombinant protein of Homo sapiens SUMO1 activating enzyme subunit 1 (SAE1), transcript variant 2, 20 µg | 20 ug |
$867.00
|
|
| TP327950 | Recombinant protein of human SUMO1 activating enzyme subunit 1 (SAE1), transcript variant 1, 20 µg | 20 ug |
$867.00
|
|