HMBS (NM_000190) Human Recombinant Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 39.1 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_000181 |
| Locus ID | 3145 |
| UniProt ID | P08397 |
| Cytogenetics | 11q23.3 |
| RefSeq Size | 1526 |
| RefSeq ORF | 1083 |
| Synonyms | PBG-D; PBGD; PORC; UPS |
| Summary | This gene encodes a member of the hydroxymethylbilane synthase superfamily. The encoded protein is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. Mutations in this gene are associated with the autosomal dominant disease acute intermittent porphyria. Alternatively spliced transcript variants encoding different isoforms have been described. provided by RefSeq, Jul 2008 |
| Protein Categories | Intracellular Proteins |
| Protein Families | Druggable Genome |
| Protein Pathways | Metabolic pathways, Porphyrin and chlorophyll metabolism |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "HMBS" proteins (7)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH301362 | HMBS MS Standard C13 and N15-labeled recombinant protein (NP_000181) | 10 ug |
$3,360.00
|
|
| PH312662 | HMBS MS Standard C13 and N15-labeled recombinant protein (NP_001019553) | 10 ug |
$3,360.00
|
|
| LC400069 | Lyophilized HMBS HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC422504 | Lyophilized HMBS HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY400069 | Transient overexpression lysate of hydroxymethylbilane synthase (HMBS), transcript variant 1 (as WB positive control) | 100 ug |
$436.00
|
|
| LY422504 | Transient overexpression lysate of hydroxymethylbilane synthase (HMBS), transcript variant 2 (as WB positive control) | 100 ug |
$436.00
|
|
| TP312662 | Recombinant protein of human hydroxymethylbilane synthase (HMBS), transcript variant 2, 20 µg | 20 ug |
$737.00
|
|
Citations
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