HMBS (NM_001024382) Human Mass Spec Standard

SKU
PH312662
HMBS MS Standard C13 and N15-labeled recombinant protein (NP_001019553)
  $3,360.00
3 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC212662
Predicted MW 37.5 kDa
Protein Sequence
Protein Sequence
>RC212662 representing NM_001024382
Red=Cloning site Green=Tags(s)

MRVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEHALEK
NEVDLVVHSLKDLPTVLPPGFTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRK
FPHLEFRSIRGNLNTRLRKLDEQQEFSAIILATAGLQRMGWHNRVGQILHPEECMYAVGQGALGVEVRAK
DQDILDLVGVLHDPETLLRCIAERAFLRHLEGGCSVPVAVHTAMKDGQLYLTGGVWSLDGSDSIQETMQA
TIHVPAQHEDGPEDDPQLVGITARNIPRGPQLAAQNLGISLANLLLSKGAKNILDVARQLNDAH

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_001019553
RefSeq Size 1428
RefSeq ORF 1032
Synonyms PBG-D; PBGD; PORC; UPS
Locus ID 3145
UniProt ID P08397
Cytogenetics 11q23.3
Summary This gene encodes a member of the hydroxymethylbilane synthase superfamily. The encoded protein is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. Mutations in this gene are associated with the autosomal dominant disease acute intermittent porphyria. Alternatively spliced transcript variants encoding different isoforms have been described. provided by RefSeq, Jul 2008
Protein Families Druggable Genome
Protein Pathways Metabolic pathways, Porphyrin and chlorophyll metabolism
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Other "HMBS" proteins (7)
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LC400069 Lyophilized HMBS HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
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LY400069 Transient overexpression lysate of hydroxymethylbilane synthase (HMBS), transcript variant 1 (as WB positive control) 100 ug
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LY422504 Transient overexpression lysate of hydroxymethylbilane synthase (HMBS), transcript variant 2 (as WB positive control) 100 ug
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TP301362 Recombinant protein of human hydroxymethylbilane synthase (HMBS), transcript variant 1, 20 µg 20 ug
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TP312662 Recombinant protein of human hydroxymethylbilane synthase (HMBS), transcript variant 2, 20 µg 20 ug
$737.00

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