RRM1 (NM_001033) Human Recombinant Protein

CAT#: TP300726

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Recombinant protein of human ribonucleotide reductase M1 (RRM1)


 Product Datasheet for 'TP300726'

 Cited in 1 publication.

  View other "RRM1" proteins (3)

USD 748.00


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Size
    • 20 ug


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Specifications

Product Data
Description Recombinant protein of human ribonucleotide reductase M1 (RRM1)
Species Human
Expression Host HEK293T
Tag C-Myc/DDK
Predicted MW 89.9 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Bioactivity Binding assay (PMID: 29765556)
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Reference Data
RefSeq NP_001024
Locus ID 6240
Refseq Size 3117
Cytogenetics 11p15.4
Refseq ORF 2376
Synonyms R1; RIR1; RR1
Summary This gene encodes the large and catalytic subunit of ribonucleotide reductase, an enzyme essential for the conversion of ribonucleotides into deoxyribonucleotides. A pool of available deoxyribonucleotides is important for DNA replication during S phase of the cell cycle as well as multiple DNA repair processes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
Protein Families Druggable Genome
Protein Pathways Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism

Citations (1)

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Other Versions

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