S adenosylhomocysteine hydrolase (AHCY) (NM_000687) Human Recombinant Protein
$737.00
In Stock*
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 47.5 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_000678 |
| Locus ID | 191 |
| UniProt ID | P23526 |
| Cytogenetics | 20q11.22 |
| RefSeq Size | 2211 |
| RefSeq ORF | 1296 |
| Synonyms | adoHcyase; SAHH |
| Summary | S-adenosylhomocysteine hydrolase belongs to the adenosylhomocysteinase family. It catalyzes the reversible hydrolysis of S-adenosylhomocysteine (AdoHcy) to adenosine (Ado) and L-homocysteine (Hcy). Thus, it regulates the intracellular S-adenosylhomocysteine (SAH) concentration thought to be important for transmethylation reactions. Deficiency in this protein is one of the different causes of hypermethioninemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Jun 2009 |
| Protein Categories | Intracellular Proteins |
| Protein Families | Druggable Genome |
| Protein Pathways | Cysteine and methionine metabolism, Metabolic pathways, Selenoamino acid metabolism |
Reviews
Documents
| FAQs |
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Resources
| Recombinant Protein Resources |
Other "S adenosylhomocysteine hydrolase" proteins (3)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH300724 | AHCY MS Standard C13 and N15-labeled recombinant protein (NP_000678) | 10 ug |
$3,360.00
|
|
| LC400228 | Lyophilized AHCY HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY400228 | Transient overexpression lysate of adenosylhomocysteinase (AHCY), transcript variant 1 (as WB positive control) | 100 ug |
$436.00
|
|
Citations
Erythropoietin Slows Photoreceptor Cell Death in a Mouse Model of Autosomal Dominant Retinitis Pigmentosa
Rex, Kasmala, Bond et al
PLoS ONE (2016) 11 (6), e0157411 DOI: 10.1371/journal.pone.0157411
Rex, Kasmala, Bond et al
PLoS ONE (2016) 11 (6), e0157411 DOI: 10.1371/journal.pone.0157411
Cited by 9
AI Summary: In this study, human Epo cDNA obtained from OriGene was used to generate the EPO-R76E gene construct for recombinant adeno-associated virus (rAAV) delivery, enabling the investigation of EPO-R76E’s protective effects on photoreceptor cell survival in a mouse model of retinitis pigmentosa.
Showing 1-1 of 1 papers.
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