CDK1 (NM_001786) Human Recombinant Protein
Recombinant protein of human cell division cycle 2, G1 to S and G2 to M (CDC2), transcript variant 1
Specifications
Product Data | |
Description | Recombinant protein of human cell division cycle 2, G1 to S and G2 to M (CDC2), transcript variant 1 |
Species | Human |
Expression Host | HEK293T |
Expression cDNA Clone or AA Sequence | Recombinant protein was produced with TrueORF clone, RC200495. Click on the TrueORF clone link to view cDNA and protein sequences. |
Tag | C-Myc/DDK |
Predicted MW | 33.9 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol |
Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_001777 |
Locus ID | 983 |
Refseq Size | 1923 |
Cytogenetics | 10q21.2 |
Refseq ORF | 891 |
Synonyms | CDC2; CDC28A; P34CDC2 |
Summary | The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009] |
Protein Families | Druggable Genome, Protein Kinase, Stem cell - Pluripotency |
Protein Pathways | Cell cycle, Gap junction, Oocyte meiosis, p53 signaling pathway, Progesterone-mediated oocyte maturation |
Documents
FAQs |
SDS |
Resources
Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC400676 | CDK1 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 110.00 |
|
LY400676 | Transient overexpression lysate of cyclin-dependent kinase 1 (CDK1), transcript variant 1 |
USD 360.00 |
|
PH300495 | CDK1 MS Standard C13 and N15-labeled recombinant protein (NP_001777) |
USD 2,260.00 |
USD 350.00
USD 345.00