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SF3B3 (NM_012426) Human Recombinant Protein

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SKU
LP309509
Lyophilized purified recombinant protein of Human splicing factor 3b, subunit 3, 130kDa (SF3B3), 20ug
Size:
20 ug
Formulation:
Lyophilized Liquid
  $867.00
2 Weeks*
Bulk/Customize

Frequently Bought Together (2)

TA308399 Rabbit polyclonal antibody to SAP130 (splicing factor 3b, subunit 3, 130kDa)
100 ul
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TA592569 DDK Rabbit monoclonal antibody, recognizing both N- and C-terminal tags
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Other products for "SF3B3 or NM_012426"

Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence from TrueORF clone, RC209509, encoding the full-length of SF3B3
Tag C-terminal Myc-DDK tag
Predicted MW 135.5 kDa
Purity > 85% as determined by SDS-PAGE and Coomassie blue staining
Buffer Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.3
Reconstitution Method It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Stability Stored at -20 to -70°C for 1 year and avoid repeated freeze-thaw cycles after receipt; After reconstitution, the protein can be stored longer at -20 to -70°C, with aliquoting for single use recommended to prevent repeated freeze-thaw.
Shipping Blue Ice
Reference Data
RefSeq NP_036558
Locus ID 23450
UniProt ID Q15393
Cytogenetics 16q22.1
RefSeq Size 9736
RefSeq ORF 3651
Synonyms RSE1; SAP130; SF3b130; STAF130
Summary This gene encodes subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 3 has also been identified as a component of the STAGA (SPT3-TAF(II)31-GCN5L acetylase) transcription coactivator-HAT (histone acetyltransferase) complex, and the TFTC (TATA-binding-protein-free TAF(II)-containing complex). These complexes may function in chromatin modification, transcription, splicing, and DNA repair. provided by RefSeq, Jul 2008
Protein Categories Intracellular Proteins
Protein Pathways Spliceosome
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Other "SF3B3" proteins (3)
SKU Description Size Price
PH309509 SF3B3 MS Standard C13 and N15-labeled recombinant protein (NP_036558) 10 ug
$3,360.00
LC415767 Lyophilized SF3B3 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY415767 Transient overexpression lysate of splicing factor 3b, subunit 3, 130kDa (SF3B3) (as WB positive control) 100 ug
$436.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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