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SF3B3 Rabbit Polyclonal Antibody

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SKU
TA308399
Rabbit polyclonal antibody to SAP130 (splicing factor 3b, subunit 3, 130kDa)
Size:
100 ul
Conjugation:
Unconjugated
  $665.00
5 Days*
Bulk/Customize

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View other "SF3B3 or NM_012426" antibodies

Specifications
Specifications
Product Data
Application IF, IHC, WB
Recommended Dilution ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:20000
Reactivity Bovine), Human (Predicted: Mouse, Rat, Zebrafish
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide corresponding to a region within amino acids 1154 and 1217 of SAP130 (Uniprot ID#Q15393)
Buffer 1XPBS, 1% BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Concentration lot specific
Purification Purified by antigen-affinity chromatography.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 136 kDa
Gene Name splicing factor 3b subunit 3
Database Link
Background This gene encodes subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 3 has also been identified as a component of the STAGA (SPT3-TAF(II)31-GCN5L acetylase) transcription coactivator-HAT (histone acetyltransferase) complex, and the TFTC (TATA-binding-protein-free TAF(II)-containing complex). These complexes may function in chromatin modification, transcription, splicing, and DNA repair. provided by RefSeq
Synonyms RSE1; SAP130; SF3b130; STAF130
Note Seq homology of immunogen across species: Mouse (100%), Rat (100%), Zebrafish (100%), Bovine (100%)
Reference Data
Protein Categories Intracellular Proteins
Protein Pathways Spliceosome
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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