COMMD5 (NM_001081003) Human Mass Spec Standard

SKU
PH316768
COMMD5 MS Standard C13 and N15-labeled recombinant protein (NP_001074472)
  $3,360.00
3 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC216768
Predicted MW 24.7 kDa
Protein Sequence
Protein Sequence
>RC216768 protein sequence
Red=Cloning site Green=Tags(s)

MSAVGAATPYLHHPGDSHSGRVSFLGAQLPPEVAAMARLLGDLDRSTFRKLLKFVVSSLQGEDCREAVQR
LGVSANLPEEQLGALLAGMHTLLQQALRLPPTSLKPDTFRDQLQELCIPQDLVGDLASVVFGSQRPLLDS
VAQQQGAWLPHVADFRWRVDVAISTSALARSLQPSVLMQLKLSDGSAYRFEVPTAKFQELRYSVALVLKE
MADLEKRCERRLQD

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_001074472
RefSeq Size 1453
RefSeq ORF 672
Synonyms HCARG; HT002
Locus ID 28991
UniProt ID Q9GZQ3
Cytogenetics 8q24.3
Summary May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (PubMed:21778237). Negatively regulates cell proliferation. Negatively regulates cell cycle G2/M phase transition probably by transactivating p21/CDKN1A through the p53/TP53-independent signaling pathway. Involved in kidney proximal tubule morphogenesis (By similarity). Down-regulates activation of NF-kappa-B (PubMed:15799966).UniProtKB/Swiss-Prot Function
Protein Families Druggable Genome
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Other "COMMD5" proteins (11)
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PH301051 COMMD5 MS Standard C13 and N15-labeled recombinant protein (NP_001074473) 10 ug
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LC415491 Lyophilized COMMD5 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
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LY415491 Transient overexpression lysate of COMM domain containing 5 (COMMD5), transcript variant 1 (as WB positive control) 100 ug
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LY421149 Transient overexpression lysate of COMM domain containing 5 (COMMD5), transcript variant 2 (as WB positive control) 100 ug
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LY421150 Transient overexpression lysate of COMM domain containing 5 (COMMD5), transcript variant 3 (as WB positive control) 100 ug
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TP301051 Recombinant protein of human COMM domain containing 5 (COMMD5), transcript variant 3, 20 µg 20 ug
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TP309381 Recombinant protein of human COMM domain containing 5 (COMMD5), transcript variant 1, 20 µg 20 ug
$867.00
TP316768 Recombinant protein of human COMM domain containing 5 (COMMD5), transcript variant 2, 20 µg 20 ug
$867.00

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