FMO5 (NM_001461) Human Mass Spec Standard
Specifications
| Product Data | |
| Tag | C-Myc/DDK |
|---|---|
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC214057 |
| Predicted MW | 60 kDa |
| Protein Sequence | |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
| Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_001452 |
| RefSeq Size | 2326 |
| RefSeq ORF | 1599 |
| Synonyms | hBVMO1 |
| Locus ID | 2330 |
| UniProt ID | P49326 |
| Cytogenetics | 1q21.1 |
| Summary | Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. Alternative splicing results in multiple transcript variants. provided by RefSeq, Jan 2009 |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Drug metabolism - cytochrome P450 |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "FMO5" proteins (5)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| LC419912 | Lyophilized FMO5 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC428524 | Lyophilized FMO5 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY419912 | Transient overexpression lysate of flavin containing monooxygenase 5 (FMO5), transcript variant 1 (as WB positive control) | 100 ug |
$665.00
|
|
| LY428524 | Transient overexpression lysate of flavin containing monooxygenase 5 (FMO5), transcript variant 2 (as WB positive control) | 100 ug |
$436.00
|
|
| TP314057 | Recombinant protein of human flavin containing monooxygenase 5 (FMO5), transcript variant 1, 20 µg | 20 ug |
$867.00
|
|
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