FMO5 (NM_001461) Human Recombinant Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 60 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_001452 |
| Locus ID | 2330 |
| UniProt ID | P49326 |
| Cytogenetics | 1q21.1 |
| RefSeq Size | 2326 |
| RefSeq ORF | 1599 |
| Synonyms | hBVMO1 |
| Summary | Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. Alternative splicing results in multiple transcript variants. provided by RefSeq, Jan 2009 |
| Protein Categories | Intracellular Proteins, Membrane Proteins |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Drug metabolism - cytochrome P450 |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "FMO5" proteins (5)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH314057 | FMO5 MS Standard C13 and N15-labeled recombinant protein (NP_001452) | 10 ug |
$3,360.00
|
|
| LC419912 | Lyophilized FMO5 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC428524 | Lyophilized FMO5 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY419912 | Transient overexpression lysate of flavin containing monooxygenase 5 (FMO5), transcript variant 1 (as WB positive control) | 100 ug |
$665.00
|
|
| LY428524 | Transient overexpression lysate of flavin containing monooxygenase 5 (FMO5), transcript variant 2 (as WB positive control) | 100 ug |
$436.00
|
|
Citations
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