NCALD (NM_001040628) Human Mass Spec Standard

CAT#: PH312908

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NCALD MS Standard C13 and N15-labeled recombinant protein (NP_001035718)

  View other "NCALD" proteins (32)

USD 2,260.00

3 Weeks

    • 10 ug

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Product Data
Description NCALD MS Standard C13 and N15-labeled recombinant protein (NP_001035718)
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC212908
Predicted MW 22.3 kDa
Protein Sequence
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration 50 ug/ml as determined by BCA
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80°C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
Reference Data
RefSeq NP_001035718
RefSeq Size 3729
RefSeq ORF 579
Locus ID 83988
UniProt ID P61601, B2RB70
Cytogenetics 8q22.3
Summary This gene encodes a member of the neuronal calcium sensor (NCS) family of calcium-binding proteins. The protein contains an N-terminal myristoylation signal and four EF-hand calcium binding loops. The protein is cytosolic at resting calcium levels; however, elevated intracellular calcium levels induce a conformational change that exposes the myristoyl group, resulting in protein association with membranes and partial co-localization with the perinuclear trans-golgi network. The protein is thought to be a regulator of G protein-coupled receptor signal transduction. Several alternatively spliced variants of this gene have been determined, all of which encode the same protein; additional variants may exist but their biological validity has not been determined. [provided by RefSeq, Jul 2008]


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