PRMT6 (NM_018137) Human Mass Spec Standard

SKU
PH309527
PRMT6 MS Standard C13 and N15-labeled recombinant protein (NP_060607)
  $3,360.00
3 Weeks*
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Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC209527
Predicted MW 35.2 kDa
Protein Sequence
Protein Sequence
>RC209527 protein sequence
Red=Cloning site Green=Tags(s)

MIADRVRTDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQAREVVRFNGL
EDRVHVLPGPVETVELPEQVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLLPASAELFIAPISDQ
MLEWRLGFWSQVKQHYGVDMSCLEGFATRCLMGHSEIVVQGLSGEDVLARPQRFAQLELSRAGLEQELEA
GVGGRFRCSCYGSAPMHGFAIWFQVTFPGGESEKPLVLSTSPFHPATHWKQALLYLNEPVQVEQDTDVSG
EITLLPSRDNPRRLRVLLRYKVGDQEEKTKDFAMED

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_060607
RefSeq Size 2665
RefSeq ORF 948
Synonyms HRMT1L6
Locus ID 55170
UniProt ID Q96LA8
Cytogenetics 1p13.3
Summary The protein encoded by this gene belongs to the arginine N-methyltransferase family, which catalyze the sequential transfer of methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins, to form methylated arginine derivatives and S-adenosyl-L-homocysteine. This protein can catalyze both, the formation of omega-N monomethylarginine and asymmetrical dimethylarginine, with a strong preference for the latter. It specifically mediates the asymmetric dimethylation of Arg2 of histone H3, and the methylated form represents a specific tag for epigenetic transcriptional repression. This protein also forms a complex with, and methylates DNA polymerase beta, resulting in stimulation of polymerase activity by enhancing DNA binding and processivity. provided by RefSeq, Sep 2011
Protein Families Druggable Genome
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Other "PRMT6" proteins (6)
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LC413290 Lyophilized PRMT6 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
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LY413290 Transient overexpression lysate of protein arginine methyltransferase 6 (PRMT6) (as WB positive control) 100 ug
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LY432201 Transient overexpression lysate of protein arginine methyltransferase 6 (PRMT6) (as WB positive control) 100 ug
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TP309527 Recombinant protein of human protein arginine methyltransferase 6 (PRMT6), 20 µg 20 ug
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TP329177 Recombinant protein of human protein arginine methyltransferase 6 (PRMT6), 20 µg 20 ug
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