PRMT6 (NM_018137) Human Mass Spec Standard
Specifications
| Product Data | |
| Tag | C-Myc/DDK |
|---|---|
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC209527 |
| Predicted MW | 35.2 kDa |
| Protein Sequence | |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
| Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_060607 |
| RefSeq Size | 2665 |
| RefSeq ORF | 948 |
| Synonyms | HRMT1L6 |
| Locus ID | 55170 |
| UniProt ID | Q96LA8 |
| Cytogenetics | 1p13.3 |
| Summary | The protein encoded by this gene belongs to the arginine N-methyltransferase family, which catalyze the sequential transfer of methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins, to form methylated arginine derivatives and S-adenosyl-L-homocysteine. This protein can catalyze both, the formation of omega-N monomethylarginine and asymmetrical dimethylarginine, with a strong preference for the latter. It specifically mediates the asymmetric dimethylation of Arg2 of histone H3, and the methylated form represents a specific tag for epigenetic transcriptional repression. This protein also forms a complex with, and methylates DNA polymerase beta, resulting in stimulation of polymerase activity by enhancing DNA binding and processivity. provided by RefSeq, Sep 2011 |
| Protein Families | Druggable Genome |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "PRMT6" proteins (6)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| LC413290 | Lyophilized PRMT6 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC432201 | Lyophilized PRMT6 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY413290 | Transient overexpression lysate of protein arginine methyltransferase 6 (PRMT6) (as WB positive control) | 100 ug |
$436.00
|
|
| LY432201 | Transient overexpression lysate of protein arginine methyltransferase 6 (PRMT6) (as WB positive control) | 100 ug |
$436.00
|
|
| TP309527 | Recombinant protein of human protein arginine methyltransferase 6 (PRMT6), 20 µg | 20 ug |
$867.00
|
|
| TP329177 | Recombinant protein of human protein arginine methyltransferase 6 (PRMT6), 20 µg | 20 ug |
$867.00
|
|
Citations
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