PRMT6 (NM_018137) Human Recombinant Protein

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TP329177
Recombinant protein of human protein arginine methyltransferase 6 (PRMT6), 20 µg
  $867.00
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Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
>RC229177 representing NM_018137
Red=Cloning site Green=Tags(s)

MSQPKKRKLESGGGGEGGEGTEEEDGAEREAALERPRRTKRERDQLYYECYSDVSVHEEMIADRVRTDAY
RLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPV
ETVELPEQVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLLPASAELFIAPISDQMLEWRLGFWSQ
VKQHYGVDMSCLEGFATRCLMGHSEIVVQGLSGEDVLARPQRFAQLELSRAGLEQELEAGVGGRFRCSCY
GSAPMHGFAIWFQVTFPGGESEKPLVLSTSPFHPATHWKQALLYLNEPVQVEQDTDVSGEITLLPSRDNP
RRLRVLLRYKVGDQEEKTKDFAMED

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag C-Myc/DDK
Predicted MW 41.8 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Preparation NULL or Add: Recombinant proteins was captured through anti-DDK affinity column followed by conventional chromatography steps.
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_060607
Locus ID 55170
UniProt ID Q96LA8
Cytogenetics 1p13.3
RefSeq ORF 1125
Synonyms HRMT1L6
Summary The protein encoded by this gene belongs to the arginine N-methyltransferase family, which catalyze the sequential transfer of methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins, to form methylated arginine derivatives and S-adenosyl-L-homocysteine. This protein can catalyze both, the formation of omega-N monomethylarginine and asymmetrical dimethylarginine, with a strong preference for the latter. It specifically mediates the asymmetric dimethylation of Arg2 of histone H3, and the methylated form represents a specific tag for epigenetic transcriptional repression. This protein also forms a complex with, and methylates DNA polymerase beta, resulting in stimulation of polymerase activity by enhancing DNA binding and processivity. provided by RefSeq, Sep 2011
Protein Categories Intracellular Proteins
Protein Families Druggable Genome
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Other "PRMT6" proteins (6)
SKU Description Size Price
PH309527 PRMT6 MS Standard C13 and N15-labeled recombinant protein (NP_060607) 10 ug
$3,360.00
LC413290 Lyophilized PRMT6 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
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LC432201 Lyophilized PRMT6 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
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LY413290 Transient overexpression lysate of protein arginine methyltransferase 6 (PRMT6) (as WB positive control) 100 ug
$436.00
LY432201 Transient overexpression lysate of protein arginine methyltransferase 6 (PRMT6) (as WB positive control) 100 ug
$436.00
TP309527 Recombinant protein of human protein arginine methyltransferase 6 (PRMT6), 20 µg 20 ug
$867.00

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