EIF4E (NM_001968) Human Mass Spec Standard

SKU
PH307333
EIF4E MS Standard C13 and N15-labeled recombinant protein (NP_001959)
  $3,360.00
3 Weeks*
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Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC207333
Predicted MW 25.1 kDa
Protein Sequence
Protein Sequence
>RC207333 protein sequence
Red=Cloning site Green=Tags(s)

MATVEPETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVE
DFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGE
SFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGST
TKNRFVV

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_001959
RefSeq Size 4749
RefSeq ORF 651
Synonyms AUTS19; CBP; eIF-4E; EIF4E1; EIF4EL1; EIF4F
Locus ID 1977
UniProt ID P06730
Cytogenetics 4q23
Summary The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5'-cap structure. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. This gene acts as a proto-oncogene, and its expression and activation is associated with transformation and tumorigenesis. Several pseudogenes of this gene are found on other chromosomes. Alternative splicing results in multiple transcript variants. provided by RefSeq, Sep 2015
Protein Pathways Insulin signaling pathway, mTOR signaling pathway
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Other "EIF4E" proteins (4)
SKU Description Size Price
LC400723 Lyophilized EIF4E HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY400723 Transient overexpression lysate of eukaryotic translation initiation factor 4E (EIF4E), transcript variant 1 (as WB positive control) 100 ug
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TP307333 Recombinant protein of human eukaryotic translation initiation factor 4E (EIF4E), transcript variant 1, 20 µg 20 ug
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TP721168 Purified recombinant protein of Human eukaryotic translation initiation factor 4E (EIF4E), transcript variant 1 10 ug
$340.00

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