EIF4E (NM_001968) Human Mass Spec Standard
Specifications
| Product Data | |
| Tag | C-Myc/DDK |
|---|---|
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC207333 |
| Predicted MW | 25.1 kDa |
| Protein Sequence | |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
| Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_001959 |
| RefSeq Size | 4749 |
| RefSeq ORF | 651 |
| Synonyms | AUTS19; CBP; eIF-4E; EIF4E1; EIF4EL1; EIF4F |
| Locus ID | 1977 |
| UniProt ID | P06730 |
| Cytogenetics | 4q23 |
| Summary | The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5'-cap structure. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. This gene acts as a proto-oncogene, and its expression and activation is associated with transformation and tumorigenesis. Several pseudogenes of this gene are found on other chromosomes. Alternative splicing results in multiple transcript variants. provided by RefSeq, Sep 2015 |
| Protein Pathways | Insulin signaling pathway, mTOR signaling pathway |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "EIF4E" proteins (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| LC400723 | Lyophilized EIF4E HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY400723 | Transient overexpression lysate of eukaryotic translation initiation factor 4E (EIF4E), transcript variant 1 (as WB positive control) | 100 ug |
$436.00
|
|
| TP307333 | Recombinant protein of human eukaryotic translation initiation factor 4E (EIF4E), transcript variant 1, 20 µg | 20 ug |
$737.00
|
|
| TP721168 | Purified recombinant protein of Human eukaryotic translation initiation factor 4E (EIF4E), transcript variant 1 | 10 ug |
$340.00
|
|
Citations
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