DUSP4 (NM_001394) Human Mass Spec Standard
$3,360.00
3 Weeks*
Specifications
| Product Data | |
| Tag | C-Myc/DDK |
|---|---|
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC200640 |
| Predicted MW | 43 kDa |
| Protein Sequence | |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
| Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_001385 |
| RefSeq Size | 5625 |
| RefSeq ORF | 1182 |
| Synonyms | HVH2; MKP-2; MKP2; TYP |
| Locus ID | 1846 |
| UniProt ID | Q13115 |
| Cytogenetics | 8p12 |
| Summary | The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, ERK2 and JNK, is expressed in a variety of tissues, and is localized in the nucleus. Two alternatively spliced transcript variants, encoding distinct isoforms, have been observed for this gene. In addition, multiple polyadenylation sites have been reported. provided by RefSeq, Jul 2008 |
| Protein Families | Phosphatase |
| Protein Pathways | MAPK signaling pathway |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "DUSP4" proteins (7)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH315252 | DUSP4 MS Standard C13 and N15-labeled recombinant protein (NP_476499) | 10 ug |
$3,360.00
|
|
| LC400543 | Lyophilized DUSP4 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC403296 | Lyophilized DUSP4 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY400543 | Transient overexpression lysate of dual specificity phosphatase 4 (DUSP4), transcript variant 1 (as WB positive control) | 100 ug |
$436.00
|
|
| LY403296 | Transient overexpression lysate of dual specificity phosphatase 4 (DUSP4), transcript variant 2 (as WB positive control) | 100 ug |
$436.00
|
|
| TP300640 | Recombinant protein of human dual specificity phosphatase 4 (DUSP4), transcript variant 1, 20 µg | 20 ug |
$737.00
|
|
| TP315252 | Recombinant protein of human dual specificity phosphatase 4 (DUSP4), transcript variant 2, 20 µg | 20 ug |
$737.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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