Plxna1 Mouse Gene Knockout Kit (CRISPR)

SKU
KN313500LP
Plxna1 - mouse gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol Plxna1
Locus ID 18844
Components

KN313500G1, Plxna1 gRNA vector 1 in pCas-Guide CRISPR vector

KN313500G2, Plxna1 gRNA vector 2 in pCas-Guide CRISPR vector

KN313500LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_008881
UniProt ID P70206
Synonyms 2600013D04Rik; mKIAA4053; NOV; PlexA1; Plxn1
Summary Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm.UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
GA203299 Plxna1 CRISPRa kit - CRISPR gene activation of mouse plexin A1 1 kit
$1,657.00
KN313500 Plxna1 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN313500BN Plxna1 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN313500RB Plxna1 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN513500 Plxna1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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