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CARD11 Human Gene Knockout Kit (CRISPR)

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SKU
KN222740BN
CARD11 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "CARD11 or NM_001324281"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol CARD11
Locus ID 84433
Components

KN222740G1, CARD11 gRNA vector 1 in pCas-Guide CRISPR vector

KN222740G2, CARD11 gRNA vector 2 in pCas-Guide CRISPR vector

KN222740BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001324281, NM_032415
UniProt ID Q9BXL7
Synonyms BENTA; BIMP3; CARMA1; IMD11; PPBL
Summary The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
GA113541 CARD11 CRISPRa kit - CRISPR gene activation of human caspase recruitment domain family member 11 1 kit
$1,657.00
KN222740 CARD11 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN222740LP CARD11 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN222740RB CARD11 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN422740 CARD11 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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