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Delta Opioid Receptor (OPRD1) Human Gene Knockout Kit (CRISPR)

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SKU
KN219275BN
OPRD1 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

Frequently Bought Together (4)

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RC219275 OPRD1 (Myc-DDK-tagged)-Human opioid receptor, delta 1 (OPRD1)
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$457.00
GE100003 pCAS-Scramble, pCas-Guide vector with a scrambled sequence as a negative control (10 µg)
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Other products for "Delta Opioid Receptor or NM_000911"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol Delta Opioid Receptor
Locus ID 4985
Components

KN219275G1, Delta Opioid Receptor gRNA vector 1 in pCas-Guide CRISPR vector

KN219275G2, Delta Opioid Receptor gRNA vector 2 in pCas-Guide CRISPR vector

KN219275BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_000911
UniProt ID P41143
Synonyms OPRD
Summary G-protein coupled receptor that functions as receptor for endogenous enkephalins and for a subset of other opioids. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain and in opiate-mediated analgesia. Plays a role in developing analgesic tolerance to morphine.UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
GA103322 OPRD1 CRISPRa kit - CRISPR gene activation of human opioid receptor delta 1 1 kit
$1,657.00
KN219275 OPRD1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN219275LP OPRD1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN219275RB OPRD1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN419275 OPRD1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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