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FGFR3 Human Gene Knockout Kit (CRISPR)

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SKU
KN215533LP
FGFR3 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "FGFR3 or NM_000142"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol FGFR3
Locus ID 2261
Components

KN215533G1, FGFR3 gRNA vector 1 in pCas-Guide CRISPR vector

KN215533G2, FGFR3 gRNA vector 2 in pCas-Guide CRISPR vector

KN215533LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_000142, NM_001163213, NM_022965, NM_001354809, NM_001354810, NR_148971
UniProt ID P22607
Synonyms ACH; CD333; CEK2; HSFGFR3EX; JTK4
Summary This gene encodes a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene lead to craniosynostosis and multiple types of skeletal dysplasia. provided by RefSeq, Aug 2017
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Documents
Resources
Other Versions
SKU Description Size Price
GA101584 FGFR3 CRISPRa kit - CRISPR gene activation of human fibroblast growth factor receptor 3 1 kit
$1,657.00
KN215533 FGFR3 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN215533BN FGFR3 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN215533RB FGFR3 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN415533 FGFR3 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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