TLR9 Human Gene Knockout Kit (CRISPR)

SKU
KN207510BN
TLR9 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol TLR9
Locus ID 54106
Components

KN207510G1, TLR9 gRNA vector 1 in pCas-Guide CRISPR vector

KN207510G2, TLR9 gRNA vector 2 in pCas-Guide CRISPR vector

KN207510BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_017442, NM_138688
UniProt ID Q9NR96
Synonyms CD289
Summary The protein encoded by this gene is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response. provided by RefSeq, Aug 2017
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Other Versions
SKU Description Size Price
GA110063 TLR9 CRISPRa kit - CRISPR gene activation of human toll like receptor 9 1 kit
$1,657.00
KN207510 TLR9 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN207510LP TLR9 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN207510RB TLR9 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN407510 TLR9 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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