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P cadherin (CDH3) Human Gene Knockout Kit (CRISPR)

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SKU
KN207346LP
CDH3 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "P cadherin or NM_001317195"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol P cadherin
Locus ID 1001
Components

KN207346G1, P cadherin gRNA vector 1 in pCas-Guide CRISPR vector

KN207346G2, P cadherin gRNA vector 2 in pCas-Guide CRISPR vector

KN207346LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001317195, NM_001317196, NM_001793
UniProt ID P22223
Synonyms CDHP; HJMD; PCAD
Summary This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene are associated with hypotrichosis with juvenile macular dystrophy and ectodermal dysplasia, ectrodactyly, and macular dystrophy syndrome (EEMS). provided by RefSeq, Nov 2015
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Other Versions
SKU Description Size Price
GA100715 CDH3 CRISPRa kit - CRISPR gene activation of human cadherin 3 1 kit
$1,657.00
KN207346 CDH3 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN207346BN CDH3 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN207346RB CDH3 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN407346 CDH3 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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