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RGS10 Human Gene Knockout Kit (CRISPR)

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SKU
KN203488BN
RGS10 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "RGS10 or NM_001005339.2"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol RGS10
Locus ID 6001
Components

KN203488G1, RGS10 gRNA vector 1 in pCas-Guide CRISPR vector

KN203488G2, RGS10 gRNA vector 2 in pCas-Guide CRISPR vector

KN203488BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001005339, NM_002925
UniProt ID O43665
Synonyms OTTHUMP00000020597; OTTHUMP00000069158; regulator of G-protein signaling 10; regulator of G-protein signalling 10
Summary Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 10 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. This protein associates specifically with the activated forms of the two related G-protein subunits, G-alphai3 and G-alphaz but fails to interact with the structurally and functionally distinct G-alpha subunits. Regulator of G protein signaling 10 protein is localized in the nucleus. Two transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
GA104095 RGS10 CRISPRa kit - CRISPR gene activation of human regulator of G protein signaling 10 1 kit
$1,657.00
KN203488 RGS10 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN203488LP RGS10 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN203488RB RGS10 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN403488 RGS10 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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