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G protein coupled receptor 30 (GPER1) Human Gene Knockout Kit (CRISPR)

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SKU
KN203027BN
GPER1 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "G protein coupled receptor 30 or NM_001031682"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol G protein coupled receptor 30
Locus ID 2852
Components

KN203027G1, G protein coupled receptor 30 gRNA vector 1 in pCas-Guide CRISPR vector

KN203027G2, G protein coupled receptor 30 gRNA vector 2 in pCas-Guide CRISPR vector

KN203027BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001031682, NM_001039966, NM_001098201, NM_001505
UniProt ID Q99527
Synonyms CMKRL2; FEG-1; GPCR-Br; LERGU; LERGU2; MGC99678
Summary This gene encodes a multi-pass membrane protein that localizes to the endoplasmic reticulum and a member of the G-protein coupled receptor 1 family. This receptor binds estrogen and activates multiple downstream signaling pathways, leading to stimulation of adenylate cyclase and an increase in cyclic AMP levels, while also promoting intracellular calcium mobilization and synthesis of phosphatidylinositol 3,4,5-trisphosphate in the nucleus. This protein therefore plays a role in the rapid nongenomic signaling events widely observed following stimulation of cells and tissues with estrogen. This receptor has been shown to play a role in diverse biological processes, including bone and nervous system development, metabolism, cognition, male fertility and uterine function. provided by RefSeq, Aug 2017
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Other Versions
SKU Description Size Price
GA101914 GPER1 CRISPRa kit - CRISPR gene activation of human G protein-coupled estrogen receptor 1 1 kit
$1,657.00
KN203027 GPER1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN203027LP GPER1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN203027RB GPER1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN403027 GPER1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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