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Mesothelin (MSLN) Human Gene Knockout Kit (CRISPR)

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SKU
KN202532LP
MSLN - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "Mesothelin or NM_001177355"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol Mesothelin
Locus ID 10232
Components

KN202532G1, Mesothelin gRNA vector 1 in pCas-Guide CRISPR vector

KN202532G2, Mesothelin gRNA vector 2 in pCas-Guide CRISPR vector

KN202532LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001177355, NM_005823, NM_013404
UniProt ID Q13421
Synonyms MPF; SMRP
Summary This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. provided by RefSeq, Feb 2016
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Documents
Resources
Other Versions
SKU Description Size Price
GA106960 MSLN CRISPRa kit - CRISPR gene activation of human mesothelin 1 kit
$1,657.00
KN202532 MSLN - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN202532BN MSLN - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN202532RB MSLN - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN402532 MSLN - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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