Mouse H2al1i activation kit by CRISPRa
Specifications
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | H2al1i |
| Locus ID | 100042946 |
| Components |
GA219035G1, H2al1i gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA219035G2, H2al1i gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA219035G3, H2al1i gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| OTI Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_001242954 |
| UniProt ID | Q5M8Q2 |
| Synonyms | ENSMUSG00000073279; Gm14475; OTTMUSG00000016780 |
| Summary | Atypical histone H2A which can replace conventional H2A in some nucleosomes and may play a role during spermatogenesis. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.UniProtKB/Swiss-Prot Function |
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