Mouse Mhrt activation kit by CRISPRa
Specifications
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | Mhrt |
| Locus ID | 791403 |
| Components |
GA218712G1, Mhrt gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA218712G2, Mhrt gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA218712G3, Mhrt gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| OTI Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NR_033497 |
| Summary | This gene encodes a spliced long non-coding RNA that may act as a cardioprotective agent in the heart. This transcript is thought to regulate chromatin remodeling by acting as a decoy to the Brg1 chromatin repressor complex thus preventing it from binding to its genomic targets. Blocking the actions of Brg1 may be crucial in protecting the heart from pathological hypertrophy. provided by RefSeq, Dec 2014 |
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