Mouse Sox1ot activation kit by CRISPRa

SKU
GA217630
Sox1ot CRISPRa kit - CRISPR gene activation of mouse Sox1 overlapping transcript
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Sox1ot
Locus ID 434280
Components

GA217630G1, Sox1ot gRNA vector 1 in pCas-Guide-GFP-CRISPRa, Target Sequence: GTTCGGGACCCTTGGACCAT

GA217630G2, Sox1ot gRNA vector 2 in pCas-Guide-GFP-CRISPRa, Target Sequence: AAAGGCGCTTCATTATGTGG

GA217630G3, Sox1ot gRNA vector 3 in pCas-Guide-GFP-CRISPRa, Target Sequence: AAGACTCGCAAGACAATTTC

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001013812, NR_027975
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Documents
Resources

file-alt Citations

Loss of the lncRNA SOX1-OT promotes p53-dependent cell-cycle arrest in astrocytes
Fuchs, Schröder, Pena et al
bioRxiv (2026)
AI Summary: OriGene contributed to this study by providing a tGFP reporter gene (GA217630) and designing the gRNA for targeting Sox1ot, which were essential tools for investigating the role of SOX1-OT in astrocyte cell-cycle regulation.
Snippet: a tGFP reporter gene were obtained 1 from Origene (GA217630) (Origene, MD, USA). A The gRNA for targeting Sox1ot was designed by Origene 4 and had the following
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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