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Mouse Obscn activation kit by CRISPRa

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SKU
GA217016
Obscn CRISPRa kit - CRISPR gene activation of mouse obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
  $1,657.00
4 Weeks*

Other products for "Obscn"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Obscn
Locus ID 380698
Components

GA217016G1, Obscn gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA217016G2, Obscn gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA217016G3, Obscn gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001003914, NM_001171512, NM_199152
Synonyms BC046431; Gm878; OTTMUSG00000005786; UNC89
Summary The obscurin gene spans more than 150 kb, contains over 80 exons and encodes a protein of approximately 800 kDa. The encoded protein contains 68 Ig domains, 2 fibronectin domains, 1 calcium/calmodulin-binding domain, 1 RhoGEF domain with an associated PH domain, and 2 serine-threonine kinase domains. This protein is one of three giant sacromeric signaling proteins that includes titin and nebulin. It may have a role in the organization of myofibrils during assembly and also may mediate interactions between the sarcoplasmic reticulum and myofibrils. Alternatively spliced transcript variants encoding different isoforms have been described although the full-length nature is not known for all splicing variants. provided by RefSeq, Jan 2010
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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